One-Quarter of Prolactinomas in Men Are Aggressive Visual Disturbances and Pituitary Hormone Deficiencies Serve as Warning Signs
Results from a multicenter study in Spain involving 41 men with prolactinomas show that 24% of these tumors are aggressive. In patients with aggressive tumors, the prevalence of visual disturbances (60% vs. 13%), TSH deficiency (70% vs. 13%), and ACTH deficiency (50% vs. 7%) was significantly higher. A stronger correlation was also observed between prolactin levels and tumor diameter in aggressive cases. These findings can aid in the early identification of aggressive tumors and inform a more aggressive therapeutic approach.
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